The Effects of Dietary w3 Fatty Acids on Platelet Composition and Function in Man: A Prospective, Controlled Study
نویسندگان
چکیده
The rarity of atherosclerotic vascular disease and a mild bruising tendency in Greenland Eskimos has been linked to their ingestion of w3 fatty acids contained in foods obtained from the sea. Previous studies have shown that feeding salmon oil to normal volunteers resulted in reductions of plasma cholesterol and triglycerides. We wished to learn whether salmon oil feeding would result in the incorporation of w3 fatty acids into platelets and whether platelet function or platelet-vessel interactions would be altered. Diets containing salmon oils led to the incorporation of eicosapentaenoic acid (C20:5 w3) into platelets (6.1 %) with a reduction in arachidonic acid (C20:4 6). The
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